About Shasqi
Shasqi is a digital first, clinical stage, biotech company, with an office in San Francisco. Our mission is to revolutionize cancer treatment with click chemistry, a 2022 Nobel Prize winning technology. Our unique CAPAC® (Click Activated Protodrugs Against Cancer) platform uses click chemistry to target high doses of cancer drugs directly to the site of the tumor while minimizing toxicity to healthy cells, potentially improving the therapeutic index.
Over the past decade, antibody-drug conjugates (ADCs) have transformed tumor-targeted drug delivery. CAPAC® builds on this foundation, changing what’s possible with an approach that expands on the advances achieved by ADCs. Shasqi has developed an expansive and diverse library of antigen targeting agents and cancer therapeutic payloads. These are decoupled from each other and reunited at the site of the tumor via a click chemistry reaction. We are the first company to use click chemistry in humans.
Shasqi Core Values:
1) Resourcefulness We are a small team, accomplishing something complex. We value efficiency, being concise, accurate, specific, over-communicate.
2) Simplicity in focus We can explore a million things but it’s valuable to focus on what you want to pursue.
3) Challenge Standards Find a balance between pushing limits and respecting the process.
4) Collaboration Maintain a collaborative environment with respectful communication.
5) Humble Confidence Be humble in both your success and your failures.
This role entails being a senior lab manager and a research scientist. The ideal candidate will have an opportunity to grow as a researcher within the biotechnology environment, to develop strong organizational skills that will be transferable to many different roles in the future, and to gain exposure to different areas of expertise in drug development.
This opportunity is based in San Francisco, CA and person must be onsite 5 days a week.
Responsibilities
- Engage in operational tasks to ensure the laboratory is running smoothly and to work at the lab bench to support in vitro research activities.
- Keep the lab in excellent order including being highly organized with physical supplies and data, sharing timely communications with R&D or other stakeholders, and managing lab instrument operation and maintenance.
- Lead inventory management including shipping and receiving materials to/from multiple vendors along with real-time tracking per quality control guidelines, effectively communicate tracking information to R&D or other stakeholders.
- Make budgetary-prudent decisions in providing the appropriate supply options to the hiring manager.
- Write experimental protocols and standard operating procedures (SOPs), as applicable.
- Responsible for training all new staff on lab procedures, proper instrument use and best practices.
- Maintain aseptic practices, manage mammalian cell cultures and run multiple basic cell-based or biochemical assays.
- Design and execute experiments independently with clear objectives that address key questions for the overall project.
- Perform data analysis with excellent attention to detail and develop presentations/reports to share with R&D or other stakeholders
- Maintain collegiate relationships with vendors, CROs and personnel from other companies sharing the laboratory space.
- Stay up to date with relevant technologies and be proactive about instituting improvements in the overall process of the project and/or lab.
- BS/MS or equivalent in cell biology, biochemistry, or related fields.
- 4+ (BS) / 2+ (MS) years of relevant work experience, preferably in the biopharmaceutical drug development setting
- 2+ years of experience as a lab manager with demonstrable organizational skills and attention to details.
- Experience reaching out and working with vendors and CROs.
- Expertise in aseptic techniques including all aspects of culturing and passaging mammalian cells.
- Skill set in running cell-based or biochemical assays or any relevant techniques that are transferable.
- Strong understanding of cell biology, processes and mechanisms, and experimental procedures.
- Demonstrable skills in designing, executing, analyzing and reporting results.
- Highly organized and independently motivated with minimal supervision.
- Strong analytical and communication skills, especially for report writing.
- Proficient at spreadsheet/database, data analysis, presentation, and documentation software.
- Be a team player and possess humility, passion, resourcefulness, independence, and good disposition.
- Experience working in cancer, tumor biology, and immunology related fields.
- Familiarity with scientific data analysis software such as GraphPad/Prism and FlowJo
- Experience drafting, writing, editing and preparing scientific publications, abstracts/posters, and management-level presentations/decks.
Benefits
Compensation and title will be commensurate with experience and responsibilities of the candidate. For a full list of employee benefits, please see Shasqi's website
We do not accept solicitations by recruiters, recruiting agencies, headhunters and outsourcing organizations.
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